Módulo 4: Questions in Evolutionary, Population, and Comparative Genomics

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Summary with important questions answered

Genomics
- Sequencing of the Human genome
- Beginning of Comparative Genomics
  - Comparative and functional genomics of eukaryotic model organisms
- Human Pangenome
- Pangenome in prokaryotes
- Open and close pangenomes
- Horizontal Gene Transfer (HGT)/ Lateral gene transfer (LGT) in Prokaryotes
- Population genomics
- Homology at the molecular level
  - Orthology Mapping – finding homologous relationships among genes in genomes
  - Identifying Orthologs: Symmetrical Best Hits / Bidirectional Best Hits (BBH)
  - Phylogenetic profiling with a reference genome
    Network / Graph Theory
BLAST- How do we identify a homologous gene in a database?
- Description Tab and Statistics
- Graphic Summary Tab
- Alignment Tab & Taxonomy Tab
HMMER 16

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